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It has been demonstrated that curcumin can act an important part in managing the protein aggregation, mitochondrial function and nitrosative/oxidative stress ( in vitro in neuronal and glial models of oxidative stress, and in vivo in male Sprague-Dawley rats

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All secondary antibodies (Alexa Fluor 488 or 594 goat anti-mouse or anti-rabbit) were from Molecular Probes, Waltham, MA, USA